Year : 2011  |  Volume : 5  |  Issue : 1  |  Page : 101-104

Mismatched transfusion of 8 AB0-incompatible units of packed red blood cells in a patient with acute intermittent porphyria

1 Klinikverbund St. Antonius und St. Josef Wuppertal, Institute for Anesthesia
2 Blood Service of the German Red Cross Centre for Transfusion Medicine Hagen
3 Department of General Surgery, Johanniter Krankenhaus Radevormwald

Correspondence Address:
Burkard Rudlof
Institute for Anesthesia, Klinikverbund St. Antonius und St. Josef Wuppertal, Vogelsangstr 106, D-42109 Wuppertal, Germany

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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1658-354X.76497

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We report on a patient with acute intermittent porphyria, who received 8 AB0 incompatible units of packed red blood cells in an emergency situation. She never showed any signs of severe intravascular haemolysis. The patient died after four weeks because of a multi-organ failure caused from the malpractice of the porphyria. The problems of bedside testing, mixing field reaction, fresh frozen plasma and molecular-genetic determination of bloodgroup were discussed.

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