Year : 2011  |  Volume : 5  |  Issue : 4  |  Page : 417-418

Accidental five fold overdose of propofol for induction in a 38-days-old infant undergoing emergency bilateral inguinal hernia repair

Department of Anesthesiology, Tabriz University of Medical Sciences, Tabriz, Iran

Correspondence Address:
Reza Taheri
Department of Anesthesiology, Children's Hospital, Tabriz University of Medical Sciences, Tabriz
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1658-354X.87273

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The induction dose of propofol is higher in younger children (2.9 mg/kg for infants younger than 2 years) than in older children (2.2 mg/kg for children 6-12 years of age). A modest reduction in systolic blood pressure often accompanies bolus administration. The major concern with propofol is the potential for propofol infusion syndrome (lactic acidosis, rhabdomyolysis, cardiac and renal failure), which is generally associated with high-dose infusion for an extended period. We report a 38-days-old male infant underwent emergency bilateral inguinal hernia repair who accidentally received a five-fold dose of propofol for induction of general anesthesia.

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