Previous article Table of Contents  Next article

Year : 2018  |  Volume : 12  |  Issue : 3  |  Page : 377-378

Depression and chronic pain

1 Department of Psychiatry; Department of Pain Medicine, Royal Perth Hospital, Perth, Australia
2 Department of Anaesthesiology Unit, Medical School, University of Western Australia, Perth, Australia

Correspondence Address:
Stephan A Schug
Department of Anaesthesiology Unit, Medical School, University of Western Australia, Perth
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/sja.SJA_69_18

Rights and Permissions
Date of Web Publication2-Jul-2018

How to cite this article:
Kostov S, Schug SA. Depression and chronic pain. Saudi J Anaesth 2018;12:377-8

How to cite this URL:
Kostov S, Schug SA. Depression and chronic pain. Saudi J Anaesth [serial online] 2018 [cited 2022 Jan 20];12:377-8. Available from:

A paper in this issue of the Saudi Journal of Anaesthesia addresses for the first time the prevalence of depression and its association with a range of sociodemographic factors in patients with chronic pain in Saudi Arabia.[1] In our opinion, this article is highly relevant in its specific national and regional setting but also on an international level.

Chronic pain is one of the biggest challenges of modern medicine, and it represents one of the most serious health burdens in the modern world.[2] By its very nature, pain always involves perceptual, emotional, and cognitive factors.[3] The clear recognition and acknowledgment of these multiple factors, going beyond tokenism, are essential in its successful management. The so-called “psychosocial” factors are often conceptualized and understood as epiphenomena and as “separate” diagnostic entities from the psychological field. However, these psychological factors are an integral part of the complex experience of pain, including on a biomedical level. Not long ago, the psychological changes accompanying depression were thought to be a result of mainly psychological rather than biological factors. More recent research has shown that pain shares to a significant degree the same or similar biological mechanisms with psychological conditions such as anxiety and depression.[4] They require assessment of the pain condition in its cultural milieu and context, including broadly defined socioeducational-psychological background. The relevance of these factors in the setting of chronic pain has been recently highlighted by Dan Carr, who suggested to “flip the curriculum” from the old term “bio-psycho-social” to the more appropriate “socio-psycho-biomedical.”[5] Understanding of pain in this way will determine the true and effective application of an integrated multidisciplinary approach to its management. This approach will help to negotiate the apparent conflict between the “cure” expected by the patient and the reality of successful management of a chronic condition.

First and foremost, the paper discussed here identifies the prevalence of depression in the studied population in Saudi Arabia and through this mirrors comparable international studies in other social and ethnic settings. Furthermore, it raises issues about important sociodemographic factors; in particular, the correlation of low socioeconomic status with higher incidence of depression. It also confirms studies done in other cultural contexts describing the elevated risk of development of an effective condition, i.e., depression, among people who have a previous psychiatric history. As a result, it emphasizes the importance of these psychosocial factors for developing depression, respectively, the indivisible interplay between “somatic” and “psychological” factors in the manifestation of chronic pain. This understanding makes obvious that management of chronic pain necessarily requires addressing the emotional and cognitive components of the pain experience and not preferentially the perceptual ones as it happens so often in clinical practice. Only then, the authors' appeal for multidisciplinary management will result in management that goes beyond the nominal tokenistic practices. A real multidisciplinary and interdisciplinary approach requires integration and coordination of the skills of the various health-care professionals to address chronic pain comprehensively.[6]

This study also raises questions, which require further studies in this field. These include more comprehensive studies regarding the assessment of these factors on a transcultural level as many of the tools used are not specifically standardized for particular cultural groups. The cultural inferences on mental health issues are well recognized, and the pitfalls of transferring instruments from one culture to another have been well documented, although often ignored.[7]

Furthermore, depression is only one of the conditions that are present along with chronic pain and influence its course. In fact, a much more common, and one could dare to say ubiquitous, condition in any ill health, is anxiety. Anxiety in its manifestations often leads to an extreme focus on biomedical symptoms and diseases, which in its own right, further adversely affects chronic pain.[8] This of course also requires further studies with a particular emphasis and attention on cultural factors, but also involving some more universal factors such as “cyberchondria” or the “Dr Google phenomenon.”[9]

We welcome and recommend this paper, notwithstanding certain limitations, clearly identified by the authors. We value this study not only for what it gives us now but also appreciate it for its potential to generate further research in the “complex experience” of chronic pain, addressing not only its perceptual side but also reaching for the emotional-cognitive dimensions and ultimately, human meaning and significance.

  References Top

Al-Maharbi S, Abolkhair AB, Al Ghamdi H, Haddara M, Tolba Y, El Kabbani A, et al. Prevalence of depression and its association with sociodemographic factors in patients with chronic pain: A cross-sectional study in a tertiary care hospital in Saudi Arabia. Saudi J Anaesth 2018;12:419-25.  Back to cited text no. 1
Rice AS, Smith BH, Blyth FM. Pain and the global burden of disease. Pain 2016;157:791-6.  Back to cited text no. 2
Keefe FJ, Rumble ME, Scipio CD, Giordano LA, Perri LM. Psychological aspects of persistent pain: Current state of the science. J Pain 2004;5:195-211.  Back to cited text no. 3
Holmes A, Christelis N, Arnold C. Depression and chronic pain. Med J Aust 2013;199:S17-20.  Back to cited text no. 4
Carr DB, Bradshaw YS. Time to flip the pain curriculum? Anesthesiology 2014;120:12-4.  Back to cited text no. 5
Stanos S, Houle TT. Multidisciplinary and interdisciplinary management of chronic pain. Phys Med Rehabil Clin N Am 2006;17:435-50, vii.  Back to cited text no. 6
Ballenger JC, Davidson JR, Lecrubier Y, Nutt DJ, Kirmayer LJ, Lépine JP, et al. Consensus statement on transcultural issues in depression and anxiety from the international consensus group on depression and anxiety. J Clin Psychiatry 2001;62 Suppl 13:47-55.  Back to cited text no. 7
Sagheer MA, Khan MF, Sharif S. Association between chronic low back pain, anxiety and depression in patients at a tertiary care centre. J Pak Med Assoc 2013;63:688-90.  Back to cited text no. 8
Mathes BM, Norr AM, Allan NP, Albanese BJ, Schmidt NB. Cyberchondria: Overlap with health anxiety and unique relations with impairment, quality of life, and service utilization. Psychiatry Res 2018;261:204-11.  Back to cited text no. 9

This article has been cited by
1 Chronic Fluoxetine Impairs the Effects of 5-HT1A and 5-HT2C Receptors Activation in the PAG and Amygdala on Antinociception Induced by Aversive Situation in Mice
Daniela Baptista-de-Souza, Lígia Renata Rodrigues Tavares, Elke Mayumi Furuya-da-Cunha, Paulo Eduardo Carneiro de Oliveira, Lucas Canto-de-Souza, Ricardo Luiz Nunes-de-Souza, Azair Canto-de-Souza
Frontiers in Pharmacology. 2020; 11
[Pubmed] | [DOI]


Previous article    Next article
    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
    Access Statistics
    Email Alert *
    Add to My List *
* Registration required (free)  

  IN THIS Article

 Article Access Statistics
    PDF Downloaded153    
    Comments [Add]    
    Cited by others 1    

Recommend this journal