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Year : 2021  |  Volume : 15  |  Issue : 2  |  Page : 230-231

Replacement of catheters with triamcinolone in fast-track knee replacement. A case series

1 Department of Anesthesia and Pain Management, Centro Nacional de Rehabilitación, Hospital de Trauma, San José, Costa Rica
2 Department of Anesthesiology and Pain Management, Mostoles University Hospital, Madrid, Spain

Correspondence Address:
Andres Rocha-Romero
Centro Nacional de Rehabilitación, Centro Nacional de Control del Dolor y Cuidados Paliativos, Hospital de trauma, Alborada, 37 Av, San Jose
Costa Rica
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/sja.sja_1208_20

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Date of Submission23-Dec-2020
Date of Decision23-Dec-2020
Date of Acceptance23-Dec-2020
Date of Web Publication01-Apr-2021

How to cite this article:
Rocha-Romero A, Ureña RA, Pérez MF. Replacement of catheters with triamcinolone in fast-track knee replacement. A case series. Saudi J Anaesth 2021;15:230-1

How to cite this URL:
Rocha-Romero A, Ureña RA, Pérez MF. Replacement of catheters with triamcinolone in fast-track knee replacement. A case series. Saudi J Anaesth [serial online] 2021 [cited 2022 Dec 9];15:230-1. Available from:


We read with great interest the recent review by Dr Krishna Prasad, G V et al.[1] about adjuvants to local anesthetics in peripheral nerve blocks. We would like to illustrate our experience with triamcinolone, as this is a widely known steroid used for chronic pain procedures, but not for acute pain management.

We present a case series of 10 patients receiving a single-shot infiltration between the popliteal artery and capsule of the knee (IPACK) and adductor canal block (ACB) with perineural triamcinolone as adjuvant for Fast-Track Knee Replacement (FTKR). All patients provided written informed consent.

Patients admitted for FTKR, received spinal anesthesia with 8 mg of levobupivacaine under intravenous sedation with midazolam. An IPACK and ACB using 20 mL of 0.25% bupivacaine with 20 mg of triamcinolone acetonide was performed, with no surgical infiltration. Nonsteroidal anti-inflammatory drugs were given to all patients as part of a multimodal analgesic regimen.

Both blocks were ultrasound-guided (GE LOGIQ TM e Portable Ultrasound Machine), using a 22 G x 80 mm echogenic needle. We used a curvilinear probe for the IPACK and a linear for the ACB. After negative aspiration, the local anesthetic mixture was injected in 2-mL increments while observing an adequate fluid spread.

For ten patients, the median Numeric Rating Scale (NRS) for rest pain was 0 at 24, 48, and 72 hours. The median NRS for dynamic pain was 2 in the same time frame, respectively. Only two patients required breakthrough opioids due to inadequate control of dynamic pain, at 12 and 60 hours, for a total oral morphine equivalent (OME) of 200 and 100, respectively. Based on a 4-point Likert scale (1, dissatisfied; 2, slightly dissatisfied; 3, slightly satisfied; 4, satisfied), this approach resulted in adequate patient satisfaction [Table 1]. Block failure was reported in one case, requiring a second block 12 h later. One week later, patients were contacted to inquire about complications. None was reported.
Table 1: Summary of patient outcomes

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There are three main methods to prolong the duration of regional anesthesia techniques: Include local anesthetic adjuncts, usually limited to 8 hours.[2] Continuous catheter infusions but requires an organized follow-up to decrease infection and migration risk. Sustained-release local anesthetic (liposomal bupivacaine), but it is expensive and not always available.

Although triamcinolone's physical and chemical compatibility with common local anesthetics and safe epidural use has been described,[3],[4] it is usually reserved for chronic pain procedures.

We see many advantages with this approach: it is cheaper than liposomal bupivacaine. It is easier to perform than continuous catheter techniques and potentially safer than continuous infusions, and finally, it has a comparable long-lasting effect.

The presented cases illustrate the efficacy and usefulness of adding triamcinolone to ACB and IPACK blocks to manage postoperative pain in FTKR. Further studies are needed to clarify the optimal dose and safety profile, and to compare this technique's efficacy with other modalities such as liposomal bupivacaine.


We thank the participants of this case report.

Financial support and sponsorship


Conflicts of interest

There are no conflicts of interest.

  References Top

Krishna Prasad GV, Khanna S, Jaishree SV. Review of adjuvants to local anesthetics in peripheral nerve blocks: Current and future trends. Saudi J Anaesth 2020;14:77-84.  Back to cited text no. 1
[PUBMED]  [Full text]  
Albrecht E, Chin KJ. Advances in regional anaesthesia and acute pain management : A narrative review. Anaesthesia 2020;75:101-10.  Back to cited text no. 2
Jackson JD, Cotton L, Turkington M, Leblanc D, Kelley S. Physical and chemical compatibility of extended-release triamcinolone acetonide (TA-ER) with common local anesthetics. Adv Ther 2019;36:652-61.  Back to cited text no. 3
Van Boxem K, Rijsdijk M, Hans G, de Jong J, Kallewaard JW, Vissers K, et al. Safe use of epidural corticosteroid injections: Recommendations of the WIP Benelux Work Group. Pain Pract 2019;19:61-92.  Back to cited text no. 4


  [Table 1]

This article has been cited by
1 Keep it simple and cheap, enhancing the quality of regional analgesia
Andrés Rocha-Romero, Ricardo Aguilar-Ureña, Mario Fajardo Perez
Regional Anesthesia & Pain Medicine. 2021; : rapm-2021-
[Pubmed] | [DOI]


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