Year : 2023  |  Volume : 17  |  Issue : 2  |  Page : 266-268

An unusual presentation of Goodpasture syndrome

1 Department of General Medicine, ESIMC and PGIMSR, Chennai, Tamil Nadu, India
2 Senior Consultant Multidisciplinary ICU, Fortis Malar Hospital, Chennai, Tamil Nadu, India
3 Consultant Pulmonologist, Fortis Malar Hospital, Chennai, Tamil Nadu, India
4 Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India

Correspondence Address:
Pranjali Kurhekar
Department of Anesthesiology, Sree Balaji Medical College and Hospital, Chrompet, Chennai - 600044, Tamil Nadu
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/sja.sja_566_22

Rights and Permissions

Goodpasture disease is an anti–glomerular basement membrane (anti-GBM) disease that manifests as progressive glomerulopathy and alveolar hemorrhage. Our case was a 68-year-old female who presented with decompensated liver disease (DCLD) with no prior history suggestive of liver disease. She had dyspnea, bilateral pitting edema, icterus with normal renal parameters, and elevated liver enzymes. Ultrasonogram revealed shrunken liver, ascites, and portal hypertension with normal renal cortex echogenicity. Over the next three days, she developed progressive oliguria, hematuria, and breathlessness, with arterial blood gas showing hypoxia with acidosis and hyperkalemia. Bronchoscopic alveolar lavage was suggestive of hemorrhagic fluid. The patient succumbed to the disease in 24 hours. Anti-GBM antibodies came positive by immunofluorescence assay which confirmed the diagnosis of Goodpasture syndrome. Unusual presentation of DCLD in our case resulted in a delay in diagnosis that could have been crucial in altering the outcome.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded20    
    Comments [Add]    

Recommend this journal