Saudi Journal of Anaesthesia

ORIGINAL ARTICLE
Year
: 2015  |  Volume : 9  |  Issue : 2  |  Page : 167--173

Comparison of intraoperative brain condition, hemodynamics and postoperative recovery between desflurane and sevoflurane in patients undergoing supratentorial craniotomy


Surya Kumar Dube1, Mihir Prakash Pandia1, Arvind Chaturvedi1, Parmod Bithal1, Hari Hara Dash2 
1 Department of Neuroanesthesiology, All India Institute of Medical Sciences, New Delhi, India
2 Department of Anesthesiology, Fortis Memorial Research Institute, Gurgaon, Haryana, India

Correspondence Address:
Dr. Mihir Prakash Pandia
Department of Neuroanesthesiology, All India Institute of Medical Sciences, 7th Floor, CN Center, New Delhi
India

Background: Post operative recovery has been reported to be faster with desflurane than sevoflurane anesthesia in previous studies. The use of desflurane is often criticized in neurosurgery due to the concerns of cerebral vasodilation and increase in ICP and studies comparing desflurane and sevoflurane in neurosurgey are scarce. So we compared the intraoperative brain condition, hemodynamics and postoperative recovery in patients undergoing elective supratentorial craniotomy receiving either desflurane or sevoflurane. Materials and Methods: Fifty three patients between 18-60yr undergoing elective supratentorial craniotomy receiving N 2 O and oxygen (60%:40%) and 0.8-1.2 MAC of either desflurane or sevoflurane were randomized to group S (Sevoflurane) or group D (Desflurane). Subdural intra cranial pressure (ICP) was measured and brain condition was assessed.. Emergence time, tracheal extubation time and recovery time were recorded. Cognitive behavior was evaluated with Short Orientation Memory Concentration Test (SOMCT) and neurological outcome (at the time of discharge) was assessed using Glasgow Outcome Score (GOS) between the two groups. Results: The emergence time [Group D 7.4 ± 2.7 minutes vs. Group S 7.8 ± 3.7 minutes; P = 0.65], extubation time [Group D 11.8 ± 2.8 minutes vs. Group S 12.9 ± 4.9 minutes; P = 0.28] and recovery time [Group D 16.4 ± 2.6 minutes vs. Group S 17.1 ± 4.8 minutes; P = 0.50] were comparable between the two groups. There was no difference in ICP [Group D; 9.1 ± 4.3 mmHg vs. Group S; 10.9 ± 4.2 mmHg; P = 0.14] and brain condition between the two groups. Both groups had similar post-operative complications, hospital and ICU stay and GOS. Conclusion: In patients undergoing elective supratentorial craniotomy both sevoflurane and desflurane had similar intra-operative brain condition, hemodynamics and post operative recovery profile.


How to cite this article:
Dube SK, Pandia MP, Chaturvedi A, Bithal P, Dash HH. Comparison of intraoperative brain condition, hemodynamics and postoperative recovery between desflurane and sevoflurane in patients undergoing supratentorial craniotomy.Saudi J Anaesth 2015;9:167-173


How to cite this URL:
Dube SK, Pandia MP, Chaturvedi A, Bithal P, Dash HH. Comparison of intraoperative brain condition, hemodynamics and postoperative recovery between desflurane and sevoflurane in patients undergoing supratentorial craniotomy. Saudi J Anaesth [serial online] 2015 [cited 2022 Dec 9 ];9:167-173
Available from: https://www.saudija.org/article.asp?issn=1658-354X;year=2015;volume=9;issue=2;spage=167;epage=173;aulast=Dube;type=0